Pub. Date : 2009 Jul
PMID : 21783975
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | New results indicate that the methylxanthine caffeine, major component of coffee and the most widely consumed pharmacologically active substance in the world, might be responsible for this phenomenon as it, and even more potently its derived primary metabolite paraxanthine, inhibits transforming growth factor (TGF)-beta-dependent and -independent synthesis of connective tissue growth factor (CTGF/CCN2) in liver parenchymal cells in vitro and in vivo. | methylxanthine | cellular communication network factor 2 | Homo sapiens |
| 2 | New results indicate that the methylxanthine caffeine, major component of coffee and the most widely consumed pharmacologically active substance in the world, might be responsible for this phenomenon as it, and even more potently its derived primary metabolite paraxanthine, inhibits transforming growth factor (TGF)-beta-dependent and -independent synthesis of connective tissue growth factor (CTGF/CCN2) in liver parenchymal cells in vitro and in vivo. | methylxanthine | cellular communication network factor 2 | Homo sapiens |