Title : Glutathione-dependent interaction of heavy metal compounds with multidrug resistance proteins MRP1 and MRP2.

Pub. Date : 2008 Jul

PMID : 21783896






1 Functional Relationships(s)
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1 The interactions of three heavy metal-containing compounds, cisplatin (CDDP), arsenic trioxide (As(2)O(3)), and mercury dichloride (HgCl(2)), with the multidrug resistance transporters MRP1 and MRP2 and the involvement of glutathione (GSH)-related processes herein were investigated. Mercuric Chloride ATP binding cassette subfamily C member 2 Canis lupus familiaris