Title : Monolayers of IEC-18 cells as an in vitro model for screening the passive transcellular and paracellular transport across the intestinal barrier: comparison of active and passive transport with the human colon carcinoma Caco-2 cell line.

Pub. Date : 2002 Jul

PMID : 21782616






1 Functional Relationships(s)
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1 P-Glycoprotein-mediated transport was characterised in Caco-2 cells by an enhanced transport of vincristine and rhodamine 123 in the basolateral to apical direction and by the inhibition of this transport by verapamil. Rhodamine 123 ATP binding cassette subfamily B member 1 Homo sapiens