Pub. Date : 2011
PMID : 21771377
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Concomitant use of omeprazole and clopidogrel was found to decrease the exposure (AUC) to clopidogrel"s active metabolite by 50% and to sharply increase platelet reactivity, as a result of inhibition by omeprazole of CYP2C19, a cytochrome P450 (CYP) enzyme. | Clopidogrel | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | Concomitant use of omeprazole and clopidogrel was found to decrease the exposure (AUC) to clopidogrel"s active metabolite by 50% and to sharply increase platelet reactivity, as a result of inhibition by omeprazole of CYP2C19, a cytochrome P450 (CYP) enzyme. | Clopidogrel | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |