Title : Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism.

Pub. Date : 2011 Sep

PMID : 21762971






2 Functional Relationships(s)
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1 TRPM8 receptor function and hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) were characterized by means of Ca(2+) imaging and spatiotemporal dynamics of phospholipase C (PLC) delta1-pleckstrin homology-green fluorescent protein, respectively. Phosphatidylinositol 4,5-Diphosphate transient receptor potential cation channel subfamily M member 8 Homo sapiens
2 TRPM8 receptor function and hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) were characterized by means of Ca(2+) imaging and spatiotemporal dynamics of phospholipase C (PLC) delta1-pleckstrin homology-green fluorescent protein, respectively. Phosphatidylinositol 4,5-Diphosphate transient receptor potential cation channel subfamily M member 8 Homo sapiens