Pub. Date : 2012 Feb 15
PMID : 21761396
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The efficacy of taxane chemotherapy for metastatic breast cancer in BRCA1 and BRCA2 mutation carriers. | taxane | BRCA1 DNA repair associated | Homo sapiens |
| 2 | BACKGROUND: We assessed the efficacy of taxane chemotherapy in BRCA1- and BRCA2-associated patients compared with sporadic metastatic breast cancer patients. | taxane | BRCA1 DNA repair associated | Homo sapiens |
| 3 | CONCLUSIONS: BRCA1-associated, HRec-negative metastatic breast cancer patients were less sensitive to taxane chemotherapy than sporadic HRec-negative patients. | taxane | BRCA1 DNA repair associated | Homo sapiens |
| 4 | HRec-positive BRCA1- and BRCA2-associated patients had a sensitivity to taxane chemotherapy similar to that of sporadic patients. | taxane | BRCA1 DNA repair associated | Homo sapiens |