Title : MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation.

Pub. Date : 2011 Sep

PMID : 21757542






1 Functional Relationships(s)
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1 Here we report on the trafficking of multiple proteins that enter cells by clathrin-independent endocytosis (CIE) and determine that a set of proteins (CD44, CD98, and CD147) found primarily in recycling tubules largely failed to reach late endosomes in HeLa cells, whereas other CIE cargo proteins, including major histocompatibility complex class I protein (MHCI), trafficked to both early endosome antigen 1 (EEA1) and late endosomal compartments in addition to recycling tubules. chlorimuron ethyl CD44 molecule (Indian blood group) Homo sapiens