Pub. Date : 2011 Aug
PMID : 21757024
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Arachidonic acid (AA) is metabolized by cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome P450 (CYP) enzymes into eicosanoids, which are involved in diverse diseases, including type 1 and type 2 diabetes. | Eicosanoids | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
2 | A recent publication has demonstrated that stabilizing the levels of epoxyeicosatrienoic acids (EETs), CYP eicosanoids, by inhibiting or deleting soluble epoxide hydrolase (sEH) improves beta-cell function and reduces beta-cell apoptosis in diabetes. | Eicosanoids | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |