Title : Evidence that clozapine directly interacts on the GABAB receptor.

Pub. Date : 2011 Sep 14

PMID : 21753741






1 Functional Relationships(s)
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1 With HEK293 cells overexpressing GABABR, we showed that clozapine had a significant increase of [3H]-CGP54626A binding at GABABR1 subunit, which provided a clue of the potential therapeutic target of clozapine. gababr gamma-aminobutyric acid type B receptor subunit 1 Homo sapiens