Pub. Date : 2011 Jul 26
PMID : 21747057
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In cultured human aortic endothelial cells exposed to 30 mmol/L glucose, we observed a similar loss of mitochondrial networks and increased expression of Fis1 and dynamin-related protein-1 (Drp1), proteins required for mitochondrial fission. | Glucose | dynamin 1 like | Homo sapiens |
2 | In cultured human aortic endothelial cells exposed to 30 mmol/L glucose, we observed a similar loss of mitochondrial networks and increased expression of Fis1 and dynamin-related protein-1 (Drp1), proteins required for mitochondrial fission. | Glucose | dynamin 1 like | Homo sapiens |
3 | Silencing Fis1 or Drp1 expression with siRNA blunted high glucose-induced alterations in mitochondrial networks, reactive oxygen species production, endothelial nitric oxide synthase activation, and cGMP production. | Glucose | dynamin 1 like | Homo sapiens |