Title : Cytosolic phospholipase A2α blockade abrogates disease during the tissue-damage effector phase of experimental autoimmune encephalomyelitis by its action on APCs.

Pub. Date : 2011 Aug 15

PMID : 21746963






1 Functional Relationships(s)
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1 Cytosolic phospholipase A(2)alpha (cPLA(2)alpha) is the rate-limiting enzyme for release of arachidonic acid, which is converted primarily to PGs via the cyclooxygenase 1 and 2 pathways and to leukotrienes via the 5-lipoxygenase pathway. Arachidonic Acid phospholipase A2, group IVA (cytosolic, calcium-dependent) Mus musculus