Title : Cellular mechanisms of the clearance function of type C receptors of atrial natriuretic factor.

Pub. Date : 1990 Dec 5

PMID : 2174430






1 Functional Relationships(s)
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Protein Name
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1 125I-ANF1-28 specifically bound to C-ANF receptors in cultured bovine vascular smooth muscle cells is internalized by a temperature-dependent process at a rate of 5% occupied receptors/min at 37 degrees C. Internalized 125I-ANF1-28 is rapidly metabolized and released to the medium as [125I]monoiodotyrosine, a process that is reversibly inhibited by NH4Cl (10 mM). Ammonium Chloride natriuretic peptide A Bos taurus