Pub. Date : 2011 Oct
PMID : 21742782
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Steroid and xenobiotic receptor (SXR) is activated by endogenous and exogenous chemicals including steroids, bile acids, and prescription drugs. | Steroids | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
2 | Steroid and xenobiotic receptor (SXR) is activated by endogenous and exogenous chemicals including steroids, bile acids, and prescription drugs. | Steroids | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
3 | SXR is highly expressed in the liver and intestine, where it regulates cytochrome P450 3A4 (CYP3A4), which in turn controls xenobiotic and endogenous steroid hormone metabolism. | Steroids | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |