Pub. Date : 2011 Aug 16
PMID : 21739997
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here we examine the effect of Cys-111 glutathionylation, a physiologically prevalent post-translational oxidative modification, on the stabilities of wild type SOD1 and two phenotypically diverse FALS mutants, A4V and I112T. | Cysteine | superoxide dismutase 1 | Homo sapiens |
2 | Our experimental and computational results show that Cys-111 glutathionylation induces structural rearrangements that modulate stability of both wild type and FALS mutant SOD1. | Cysteine | superoxide dismutase 1 | Homo sapiens |