Title : TPA inhibits insulin stimulated PIP hydrolysis in fat cell membranes: evidence for modulation of insulin dependent phospholipase C by proteinkinase C.

Pub. Date : 1990 Oct 30

PMID : 2173567






1 Functional Relationships(s)
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1 In order to determine whether phorbol esters might inhibit insulin signalling also at the level of a phospholipase C, we studied the insulin dependent [3H] phosphatidylinositol 4-monophosphate (PIP) hydrolysis of fat cell membranes. Phorbol Esters insulin Homo sapiens