Title : Rapamycin is a potent inhibitor of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.

Pub. Date : 2011 Jul

PMID : 21733825






2 Functional Relationships(s)
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1 During the process of skin tumor promotion induced by treatment with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA), activation of epidermal Akt occurs as well as several downstream effectors of Akt, including the activation of mTORC1. Tetradecanoylphorbol Acetate thymoma viral proto-oncogene 1 Mus musculus
2 During the process of skin tumor promotion induced by treatment with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA), activation of epidermal Akt occurs as well as several downstream effectors of Akt, including the activation of mTORC1. Tetradecanoylphorbol Acetate thymoma viral proto-oncogene 1 Mus musculus