Title : Calpain inhibitors stimulate phagocyte functions via activation of human formyl peptide receptors.

Pub. Date : 2011 Sep 1

PMID : 21723247






2 Functional Relationships(s)
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1 HEK-293 cells stably expressing human formyl peptide receptor (hFPR) or hFPR-like 1 (hFPRL1) displayed stimulus-specific increase in [Ca(2+)](i) in response to calpain inhibitors (PD150606, PD151746, ALLN, ALLM, MG-132, and calpeptin), gamma-secretase inhibitor I, and N-formyl-Met-Leu-Phe. N-Formylmethionine Leucyl-Phenylalanine formyl peptide receptor 1 Homo sapiens
2 HEK-293 cells stably expressing human formyl peptide receptor (hFPR) or hFPR-like 1 (hFPRL1) displayed stimulus-specific increase in [Ca(2+)](i) in response to calpain inhibitors (PD150606, PD151746, ALLN, ALLM, MG-132, and calpeptin), gamma-secretase inhibitor I, and N-formyl-Met-Leu-Phe. N-Formylmethionine Leucyl-Phenylalanine formyl peptide receptor 1 Homo sapiens