Pub. Date : 2011 Jul 8
PMID : 21722948
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These findings highlight a dual role for TDG in promoting proper epigenetic states during development and suggest a two-step mechanism for DNA demethylation in mammals, whereby 5-methylcytosine and 5-hydroxymethylcytosine are first deaminated by AID to thymine and 5-hydroxymethyluracil, respectively, followed by TDG-mediated thymine and 5-hydroxymethyluracil excision repair. | 5-Methylcytosine | activation induced cytidine deaminase | Homo sapiens |