Title : Triiodothyronine stimulates transcription of the fatty acid synthase gene in chick embryo hepatocytes in culture. Insulin and insulin-like growth factor amplify that effect.

Pub. Date : 1990 Oct 25

PMID : 2170411






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Triiodothyronine stimulates transcription of the fatty acid synthase gene in chick embryo hepatocytes in culture. Triiodothyronine fatty acid synthase Gallus gallus
2 In chick embryo hepatocytes in culture, the stimulatory effect of feeding on fatty acid synthase activity is mimicked by adding triiodothyronine and insulin; the inhibitory effect of starvation is mimicked by adding glucagon or cyclic AMP. Triiodothyronine fatty acid synthase Gallus gallus
3 We now show that triiodothyronine alone stimulates transcription of fatty acid synthase by 4- to 6-fold, about the same as the increase in fatty acid synthase mRNA. Triiodothyronine fatty acid synthase Gallus gallus