Title : The tandem chain extension aldol reaction used for synthesis of ketomethylene tripeptidomimetics targeting hPEPT1.

Pub. Date : 2011 Aug 1

PMID : 21703856






1 Functional Relationships(s)
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1 The six investigated compounds were all defined as high affinity ligands (K(i)-values <0.5 mM) for hPEPT1 by measuring the concentration dependent inhibition of apical [(14)C]Gly-Sar uptake in Caco-2 cells. Glycine solute carrier family 15 member 1 Homo sapiens