Title : Induction of CCAAT/enhancer-binding protein-homologous protein by cigarette smoke through the superoxide anion-triggered PERK-eIF2α pathway.

Pub. Date : 2011 Sep 5

PMID : 21703327






1 Functional Relationships(s)
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1 These results suggest that O(2)(-) and ONOO(-) are selectively involved in CSE-triggered induction of CHOP and that the PERK-eIF2alpha pathway plays a crucial role in the induction of CHOP and apoptosis downstream of the particular reactive oxygen species. Reactive Oxygen Species DNA damage inducible transcript 3 Homo sapiens