Title : 15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes.

Pub. Date : 2011 Aug

PMID : 21699992






1 Functional Relationships(s)
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1 Cultured preadipocytes enhance the synthesis of prostaglandin (PG) E(2) and PGF(2alpha) involving the induction of cyclooxygenase (COX)-2 during the growth phase upon stimulation with a mixture of phorbol 12-myristate 13-acetate, a mitogenic factor, and calcium ionophore A23187. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens