Pub. Date : 2012 Jan 15
PMID : 21685825
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GW0742, a high-affinity PPAR-delta agonist, mediates protection in an organotypic model of spinal cord damage. | GW0742 | peroxisome proliferator activator receptor delta | Mus musculus |
| 2 | OBJECTIVE: To clarify the protective mechanism of PPAR-delta agonist GW0742 in the injured spinal cord using an in vitro model. | GW0742 | peroxisome proliferator activator receptor delta | Mus musculus |
| 3 | CONCLUSION: GW0742 reduces the cellular and molecular changes occurring in SCI by targeting different downstream pathways modulating PPAR-delta receptors. | GW0742 | peroxisome proliferator activator receptor delta | Mus musculus |