Title : Tumour topoisomerase II alpha protein expression and outcome after adjuvant dose-dense anthracycline-based chemotherapy.

Pub. Date : 2012 Jan

PMID : 21681601






2 Functional Relationships(s)
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1 The expression of topoisomerase II alpha (TOP2A) protein in 3 cohorts of breast cancers treated with adjuvant dose-dense anthracycline-based chemotherapy was determined retrospectively. Anthracyclines DNA topoisomerase II alpha Homo sapiens
2 A higher sensitivity to anthracycline-containing regimens is suggested in ER/PR-negative and TOP2A-positive cancers. Anthracyclines DNA topoisomerase II alpha Homo sapiens