Title : Preservation of acute pain and efferent functions following intrathecal resiniferatoxin-induced analgesia in rats.

Pub. Date : 2011 Sep

PMID : 21680254






4 Functional Relationships(s)
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Protein Name
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1 UNLABELLED: Resiniferatoxin (RTX) is a potent agonist of TRPV1, which possesses unique properties that can be utilized to treat certain modalities of pain. resiniferatoxin transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus
2 UNLABELLED: Resiniferatoxin (RTX) is a potent agonist of TRPV1, which possesses unique properties that can be utilized to treat certain modalities of pain. resiniferatoxin transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus
3 administration of RTX prevented TRPV1-induced nocifensive behavior and inflammatory thermal hypersensitivity. resiniferatoxin transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus
4 PERSPECTIVE: Localized administration of RTX in spinal cord could be a useful strategy to treat chronic debilitating pain arising from certain conditions such as cancer and at the same time could maintain normal physiological peripheral efferent functions mediated by TRPV1. resiniferatoxin transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus