Pub. Date : 2011 Oct
PMID : 21677657
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to assess the association between G972R polymorphism of the insulin receptor substrate-1 (IRS-1) gene and the circadian variation in blood pressure, insulin sensitivity and salt sensitivity in subjects with uncomplicated, never-treated essential hypertension receiving low-, normal- and high-salt diets. | Salts | insulin | Homo sapiens |
| 2 | The aim of this study was to assess the association between G972R polymorphism of the insulin receptor substrate-1 (IRS-1) gene and the circadian variation in blood pressure, insulin sensitivity and salt sensitivity in subjects with uncomplicated, never-treated essential hypertension receiving low-, normal- and high-salt diets. | Salts | insulin | Homo sapiens |
| 3 | On a high-salt diet, patients with the G972R polymorphism had an increased risk for insulin resistance (odds ratio (OR)=11.42, 95% confidence interval (CI) 7.68-28.44), salt sensitivity (OR=5.38, 95% CI 1.14-25.34) and non-dipper hypertension (OR=3.6, 95% CI 1.07-12.09). | Salts | insulin | Homo sapiens |