Title : The role of calcineurin/NFAT in SFRP2 induced angiogenesis--a rationale for breast cancer treatment with the calcineurin inhibitor tacrolimus.

Pub. Date : 2011

PMID : 21673995






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The FK506-FKBP12 complex associates with calcineurin and inhibits its phosphatase activity, resulting in inhibition of nuclear translocation of nuclear factor of activated T-cells (NFAT). Tacrolimus FKBP prolyl isomerase 1A pseudogene 3 Homo sapiens