Pub. Date : 2011 Aug 5
PMID : 21665948
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Among a panel of B cell lines, expression of GM1 was negatively correlated with and suppressed by gene expression of CD77 synthase (CD77Syn), whereas no significant positive correlation was found for enzymes actually biosynthesizing GM1. | G(M1) Ganglioside | alpha 1,4-galactosyltransferase (P blood group) | Homo sapiens |
| 2 | Among a panel of B cell lines, expression of GM1 was negatively correlated with and suppressed by gene expression of CD77 synthase (CD77Syn), whereas no significant positive correlation was found for enzymes actually biosynthesizing GM1. | G(M1) Ganglioside | alpha 1,4-galactosyltransferase (P blood group) | Homo sapiens |
| 3 | Unexpectedly, a GM1-suppressive phenotype was also observed in the expression of catalytically inactive CD77Syn, ruling out catalytic consumption of lactosylceramide (LacCer) as the main cause for such negative regulation. | G(M1) Ganglioside | alpha 1,4-galactosyltransferase (P blood group) | Homo sapiens |