Title : Agents that elevate cAMP stimulate DNA fragmentation in thymocytes.

Pub. Date : 1990 Aug 15

PMID : 2166110






1 Functional Relationships(s)
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1 Agents previously shown to stimulate protein kinase C and to inhibit Ca2(+)-dependent, TCR-mediated thymocyte apoptosis, including IL-1, also blocked both DNA fragmentation and cell death in response to cAMP, suggesting interactions ("cross-talk") between the two protein kinase systems. Cyclic AMP interleukin 1 alpha Homo sapiens