Title : Cotargeting cyclin D1 starts a new chapter in lung cancer prevention and therapy.

Pub. Date : 2011 Jun

PMID : 21636543






1 Functional Relationships(s)
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1 Combining erlotinib and bexarotene, however, to cotarget cyclin D1 via the retinoid X receptor and EGFR was active preclinically in KRAS-driven lung cancer cells derived from transgenic mice and in two clinical studies in lung cancer (including wild-type EGFR tumors, with or without KRAS mutations), as reported in this issue of the journal by Dragnev and colleagues (beginning on page 818). Bexarotene cyclin D1 Mus musculus