Title : Identification of xanthones as selective killers of cancer cells overexpressing the ABC transporter MRP1.

Pub. Date : 2011 Aug 1

PMID : 21634011






1 Functional Relationships(s)
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1 Among the xanthones studied, 1,3-dihydroxy-6-methoxyxanthone was identified as the most active derivative, able to specifically kill cells transfected with human MRP1 with even greater potency than verapamil. 9H-Xanthen-9-one,1,3-dihydroxy-6-methoxy- ATP binding cassette subfamily B member 1 Homo sapiens