Pub. Date : 1990 Jul 12
PMID : 2163024
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Effects of theophylline on erythropoietin production in normal subjects and in patients with erythrocytosis after renal transplantation. | Theophylline | erythropoietin | Homo sapiens |
2 | RESULTS: After an eight-week course of theophylline treatment, the mean (+/- SEM) serum erythropoietin levels were significantly reduced in both the renal-transplant recipients (from 60 +/- 14 units per liter at base line to 9 +/- 7 units after treatment; P less than 0.05) and the normal subjects (from 6.9 +/- 0.8 units per liter at base line to 4.7 +/- 0.5 units per liter after treatment; P less than 0.05). | Theophylline | erythropoietin | Homo sapiens |
3 | CONCLUSIONS: Theophylline attenuates the production of erythropoietin in both normal subjects and patients with erythrocytosis after renal transplantation and may be useful in the treatment of the latter condition. | Theophylline | erythropoietin | Homo sapiens |