Pub. Date : 2011
PMID : 21625424
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | All three drugs induced potassium efflux from the cells as a known mechanism for NLRP3 activation but the P2X7 receptor was not required for this process. | Potassium | NLR family, pyrin domain containing 3 | Mus musculus |
| 2 | Together, the polyene macrolides amphotericin B, nystatin, and natamycin trigger IL-1beta secretion by causing potassium efflux from which activates the NLRP3-ASC-caspase-1. | Potassium | NLR family, pyrin domain containing 3 | Mus musculus |