Title : Opioids modulate interleukin-1 production and secretion by bone-marrow macrophages.

Pub. Date : 1990 May

PMID : 2162329






3 Functional Relationships(s)
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1 However, some of the opioids potentiated IL-1 production and release in macrophages concomitantly stimulated by lipopolysaccharide (LPS) or silica. Silicon Dioxide interleukin 1 alpha Homo sapiens
2 LPS induced predominantly intracellular IL-1 activity, whereas most of the silica-induced IL-1 was released extracellularly. Silicon Dioxide interleukin 1 alpha Homo sapiens
3 beta-Endorphin, leucine-enkephalin (leu-enkephalin) and beta-neoendorphin all potentiated both intracellular and extracellular release of IL 1 induced by either LPS or silica. Silicon Dioxide interleukin 1 alpha Homo sapiens