Pub. Date : 2011 Sep
PMID : 21621776
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: Cholesterol crystals have been shown to cause inflammation, and ultimately atherosclerotic lesions through the activation of the NLRP3 inflammasome. | Cholesterol | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | As cholesterol crystals have also been found in the walls of patients with abdominal aortic aneurysms (AAA), it is possible that the NLRP3 inflammasome is involved in AAA and genetic variability within this protein complex could alter disease risk. | Cholesterol | NLR family pyrin domain containing 3 | Homo sapiens |