Title : Cocaine and its derivatives blunt neutrophil functions without influencing phosphorylation of a 47-kilodalton component of the reduced nicotinamide-adenine dinucleotide phosphate oxidase.

Pub. Date : 1990 Jun 15

PMID : 2161879






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Peak levels of intracellular Ca2+ ([Ca]i) at 5 to 10 s, and levels of [Ca]i 120 s after FMLP in Fura 2-loaded cells were significantly lower in cells treated with lidocaine, findings that could be explained by enhanced 45Ca2+ efflux from neutrophils. Fura-2 formyl peptide receptor 1 Homo sapiens