Pub. Date : 1990 May 1
PMID : 2160283
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytochrome P-450 involvement in the NADPH-dependent lipid peroxidation in human placental mitochondria. | NADP | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | The NADPH-dependent lipid peroxidation in human placental mitochondria has been found to be inhibited strongly by amphenone B, aminoglutethimide and carbon monoxide, inhibitors of cytochrome P-450-mediated reactions, but was hardly affected by respiratory chain inhibitors. | NADP | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 3 | Cytochrome c, an exogenous electron acceptor which is known to compete with cytochrome P-450 for the reducing equivalents, showed an inhibitory effect on NADPH-dependent lipid peroxidation. | NADP | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 4 | These data provide evidence that cytochrome P-450 is involved in NADPH-dependent mitochondrial lipid peroxidation. | NADP | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 5 | It is suggested that superoxide liberated from cytochrome P-450, in combination with iron, may be responsible for initiation of NADPH-dependent lipid peroxidation in human placental mitochondria. | NADP | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |