Title : Interleukins 1α and 1β as regulators of steroidogenesis in human NCI-H295R adrenocortical cells.

Pub. Date : 2011 Sep-Oct

PMID : 21600230






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Both IL-1alpha and IL-1beta increased cortisol, androstenedione, dehydroepiandrosterone and dehydroepiandrosterone sulfate production, and the accumulation of mRNAs for steroidogenic acute regulatory protein (STAR), 17alpha-hydroxylase/17,20-lyase (CYP17A1) and 3beta-hydroxysteroid dehydrogenase 2 (HSD3B2) in these cells (P<0.05 for all). Androstenedione interleukin 1 alpha Homo sapiens