Title : [Pathophysiological mechanisms underlying cryopyrin-associated periodic syndromes: genetic and molecular basis and the inflammasome].

Pub. Date : 2011 Jan

PMID : 21596183






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cryopyrin recruits different adaptor and effectors proteins into a cytosolic macromolecular complex termed Nalp3-inflammasome, which senses both several pathogen-associated and damage-associated molecular patterns as well as inorganic particles (asbestos, silica), and triggers innate immune and inflammatory responses. Silicon Dioxide NLR family pyrin domain containing 3 Homo sapiens
2 Cryopyrin recruits different adaptor and effectors proteins into a cytosolic macromolecular complex termed Nalp3-inflammasome, which senses both several pathogen-associated and damage-associated molecular patterns as well as inorganic particles (asbestos, silica), and triggers innate immune and inflammatory responses. Silicon Dioxide NLR family pyrin domain containing 3 Homo sapiens