Title : Inhibition of microsomal lipid peroxidation and cytochrome P-450-catalyzed reactions by beta-lapachone and related naphthoquinones.

Pub. Date : 1990 Apr 1

PMID : 2157443






1 Functional Relationships(s)
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1 These observations support the hypothesis that, in the micromolar concentration range, o-naphthoquinones inhibit microsomal lipid peroxidation and cytochrome P-450-catalyzed reactions, by diverting reducing equivalents from NADPH to dioxygen. NADP cytochrome P450 family 4 subfamily F member 3 Homo sapiens