Title : High-dose methotrexate with R-CHOP therapy for the treatment of patients with primary central nervous system lymphoma.

Pub. Date : 2011 Jun

PMID : 21573892






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1 We describe MR-CHOP therapy, a novel treatment regimen consisting of high-dose methotrexate and R-CHOP that provides systemic anti-tumor activity with penetration of the blood-brain barrier in patients with newly diagnosed primary central nervous system lymphoma. Methotrexate DNA damage inducible transcript 3 Homo sapiens