Title : Highly selective c-Jun N-terminal kinase (JNK) 3 inhibitors with in vitro CNS-like pharmacokinetic properties II. Central core replacement.

Pub. Date : 2011 Jun 15

PMID : 21570836






1 Functional Relationships(s)
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1 Strong SAR was found for substitution of the naphthalene ring, as well as for inhibitors adopting different central scaffolds. naphthalene sarcosine dehydrogenase Homo sapiens