Title : Modulation of lipopolysaccharide-mediated cytokine secretions by retinoic Acid.

Pub. Date : 1994 Apr

PMID : 21566987






4 Functional Relationships(s)
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1 The stimulation of t-RA on LPS-mediated G-CSF secretion was dose-dependent and was observed at t-RA concentration of as low as 10(-10) M. Some other retinoids were also as effective as t-RA, whereas other steroids were either less or not effective or inhibitory on LPS-mediated G-CSF secretion. Tretinoin colony stimulating factor 3 Homo sapiens
2 The stimulation of t-RA on LPS-mediated G-CSF secretion was dose-dependent and was observed at t-RA concentration of as low as 10(-10) M. Some other retinoids were also as effective as t-RA, whereas other steroids were either less or not effective or inhibitory on LPS-mediated G-CSF secretion. Tretinoin colony stimulating factor 3 Homo sapiens
3 The stimulation of t-RA on LPS-mediated G-CSF secretion was dose-dependent and was observed at t-RA concentration of as low as 10(-10) M. Some other retinoids were also as effective as t-RA, whereas other steroids were either less or not effective or inhibitory on LPS-mediated G-CSF secretion. Tretinoin colony stimulating factor 3 Homo sapiens
4 Further experiments indicated that interleukin 1 (IL-1), one of the mediators of LPS activity, also synergized with t-RA to stimulate G-CSF secretion. Tretinoin colony stimulating factor 3 Homo sapiens