Title : Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network.

Pub. Date : 2011 Jul 1

PMID : 21565980






1 Functional Relationships(s)
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1 DNA-damaging chemotherapeutics, such as etoposide, activate a functional loop linking SIRT1 and p53 through the induction of miR-34a. Etoposide tumor protein p53 Homo sapiens