Pub. Date : 2011 Jun 14
PMID : 21563828
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we demonstrate that purified recombinant human ADAM17 is able to cleave a 20-amino acid peptide mimetic corresponding to the extracellular juxtamembrane region of human ACE2 between Arg(708) and Ser(709). | Arginine | angiotensin converting enzyme 2 | Homo sapiens |
| 2 | In summary, we have demonstrated that ADAM17 is able to cleave ACE2 peptide sequence analogues between Arg(708) and Ser(709). | Arginine | angiotensin converting enzyme 2 | Homo sapiens |
| 3 | These findings also indicate that Arg(708) and Arg(710) play a role in site recognition in the regulation of ACE2 ectodomain shedding mediated by ADAM17. | Arginine | angiotensin converting enzyme 2 | Homo sapiens |
| 4 | These findings also indicate that Arg(708) and Arg(710) play a role in site recognition in the regulation of ACE2 ectodomain shedding mediated by ADAM17. | Arginine | angiotensin converting enzyme 2 | Homo sapiens |