Title : β2-Adrenergics in hypoxia desensitize receptors but blunt inhibition of reabsorption in rat lungs.

Pub. Date : 2011 Nov

PMID : 21562317






2 Functional Relationships(s)
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1 These results indicate that prolonged alveolar hypoxia and treatment with terbutaline impaired beta2AR signaling in alveolar epithelia and in whole lungs, and this signaling was not further impaired by hypoxia. Terbutaline adrenoceptor beta 2 Rattus norvegicus
2 Despite impaired beta2AR signaling, treatment with terbutaline for 4 days prevented the inhibition of alveolar reabsorption caused by in vivo hypoxia. Terbutaline adrenoceptor beta 2 Rattus norvegicus