Pub. Date : 2012 Mar
PMID : 21561730
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Valproic acid increases SMN2 expression and modulates SF2/ASF and hnRNPA1 expression in SMA fibroblast cell lines. | Valproic Acid | survival of motor neuron 2, centromeric | Homo sapiens |
| 2 | Valproic acid (VPA) is a histone deacetylase inhibitor that can increase SMN levels in some SMA cells or SMA patients through activation of SMN2 transcription or splicing correction of SMN2 exon 7. | Valproic Acid | survival of motor neuron 2, centromeric | Homo sapiens |
| 3 | Valproic acid (VPA) is a histone deacetylase inhibitor that can increase SMN levels in some SMA cells or SMA patients through activation of SMN2 transcription or splicing correction of SMN2 exon 7. | Valproic Acid | survival of motor neuron 2, centromeric | Homo sapiens |
| 4 | Valproic acid (VPA) is a histone deacetylase inhibitor that can increase SMN levels in some SMA cells or SMA patients through activation of SMN2 transcription or splicing correction of SMN2 exon 7. | Valproic Acid | survival of motor neuron 2, centromeric | Homo sapiens |
| 5 | Valproic acid (VPA) is a histone deacetylase inhibitor that can increase SMN levels in some SMA cells or SMA patients through activation of SMN2 transcription or splicing correction of SMN2 exon 7. | Valproic Acid | survival of motor neuron 2, centromeric | Homo sapiens |
| 6 | We observed that in two fibroblast cell lines from Japanese SMA patients, more than 1mM of VPA increased SMN2 expression at both the transcript and protein levels. | Valproic Acid | survival of motor neuron 2, centromeric | Homo sapiens |