Title : Effects of interleukin-6 (IL-6) and an anti-IL-6 monoclonal antibody on drug-metabolizing enzymes in human hepatocyte culture.

Pub. Date : 2011 Aug

PMID : 21555507






1 Functional Relationships(s)
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1 IL-6 suppressed induction of CYP1A2 enzyme activity by omeprazole and CYP3A4 enzyme activity by rifampicin but only at supraphysiological concentrations of IL-6. Rifampin interleukin 6 Homo sapiens