Title : Deficiency of huntingtin has pleiotropic effects in the social amoeba Dictyostelium discoideum.

Pub. Date : 2011 Apr

PMID : 21552328






1 Functional Relationships(s)
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1 In Dictyostelium, huntingtin deficiency is compatible with survival of the organism but renders cells sensitive to low osmolarity, which produces pleiotropic cell autonomous defects that affect cAMP signaling and as a consequence development. Cyclic AMP huntingtin Mus musculus