Title : Expression of CYP3A5 and P-glycoprotein in renal allografts with histological signs of calcineurin inhibitor nephrotoxicity.

Pub. Date : 2011 May 27

PMID : 21544031






1 Functional Relationships(s)
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1 CONCLUSIONS: Based on retrospectively collected data of 103 renal transplant recipients receiving tacrolimus in combination with mycophenolate mofetil and corticosteroids, we found that renal expression and localization of CYP3A5 but not P-gp is associated with the occurrence of CNIT. Mycophenolic Acid cytochrome P450 family 3 subfamily A member 5 Homo sapiens